Broad coverage of the role of genetics in medicine, with a focus on the application of genomic technologies to the understanding of human disease. Areas covered include genomics, the identification of human disease genes, genetic disease therapies, gene editing technologies, drug development, risk assessment and genetic counseling, biochemical genetics, imprinting, mitochondrial genetics, complex inheritance, assisted reproduction, prenatal diagnosis, immunity, cancer, clinical cytogenetics, and pharmacogenetics. The profound ethical and legal considerations raised by modern genetic technologies will also be discussed. Topics will be reinforced with weekly reading assignments from the primary literature. Prerequisite: Bio 2960 and Bio 2970, or permission of instructor. Biochemistry recommended. Class limit of 30.
Course Attributes: FA NSM; BU SCI; AR NSM; AS NSM