The purpose of the Metabolism Journal Club is to introduce the graduate students to advanced topics spanning the biochemistry, cell biology and genetics of cellular and whole body metabolism, as well as metabolism in human and model diseases. Under the guidance of the course directors (Drs. Remedi and Piston), students will select recent topical articles for discussion in the weekly journal club. Students will be expected to provide a succinct introduction to the topic and lead discussion of the data presented in the journal article. For course credit, students are required to lead a paper discussion once per semester and attend to 80% of the sessions. Active participation offers the opportunity for students to hone their critical thinking and presentation skills.