Roger Beachy

Professor ​Emeritus of Biology
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    • Washington University
    • CB 1137
    • One Brookings Drive
    • St. Louis, MO 63130-4899
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    Research in Professor Beachy's laboratory is directed to understanding how plant viruses cause disease and to developing novel strategies to reduce the consequences of virus infection.

    Professor Beachy's research attempts to understand how plant viruses cause disease and works toward developing novel strategies to reduce the consequences of virus infection. The three major research topics in the lab include: (1) studies of the molecular structure and cellular mechanisms that characterize coat protein mediated resistance against tobacco mosaic virus (TMV); (2) the cellular, biochemical, and genetic components that influence cell-cell spread of TMV; and (3) the biochemical activity of host transcription factors that control expression of rice tungro bacilliform badnavirus. Studies in this laboratory encourage students and post-doctoral associates to include computational, biochemical, cellular biology, and genetics in their research.


    Selected Publications

    Beachy, R.N., Heinlein, M. (2000) Role of P30 in replication and spread of TMV. Traffic 1: 540-544.

    Qu, C., Liljas, L., Opalka, N., Brugidou, C., Yeager, M., Beachy, R.N., Fauquet, C.M., Johnson, J.E., Lin, T. (2000) 3D domain swapping modulates the stability of members of an icosahedral virus group. Structure Fold Des. 8: 1095-1103.

    Pertuccelli, S., Dai, S., Carcamo, R., Yin, Y., Chen, S., Deachy, R.N. (2001) Transcription factor RF2s alters expression of the rice tungro bacilliform virus promoter in transgenic tobacco plants. Proc. Natl. Acad. Sci. USA 98: 7675-7640.

    Kotilzky, G., Katz, A., van der Laak, J., Boyko, V., Lapidot, M., Beachy, R.N., Heinlein, M., Epel, B. (2001) A dysfunctional movement protein of tobacco mosaic virus interferes with targeting of wild-type movement protein to microtubules. Mol. Plant-Microbe Interact. 14: 895-904.